Host Species: | Rabbit |
Concentration: | 1 mg/ml (OD 1.35 / 280 nm) |
Antigen: | Recombinant Irisin constructed from the coding sequence of mouse (NM 027402.3). |
Purification: | Affinity purified |
Buffer: | 75 mM Sodium Phosphate, 75 mM NaCl, 0.5 mM EDTA, 0.02% NaN3, pH 7.2 |
Specificity | Mouse, Human. Dilution for Immunoblot & ELISA range: 1,000 to 4,000. Centrifuge before use. |
Use: | The antibody can be used for detection of Irisin in plasma, immunosassays, immunoblots. |
Storage: | -20°C for long-term storage, 4°C for short- term storage. Aliquot to avoid repeated freezing and thawing. |
*These products are for research or manufacturing use only, not for use in human therapeutic or diagnostic applications.
The exercise-inducible myokine Irisin (Boström, et al. 2012) is secreted by cleavage from the transmembrane precursor, FNDC5. Circulating Irisin govern a wide variety of cellular processes relevant to browning, angiogenesis, wound healing, bone mass, and metabolism.
Boström, et al. 2012. A PGC1-α-dependent myokine that drive brown-fat-like development of white fat and thermogenesis. Nature, 481: 463-468
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