*These products are for research or manufacturing use only, not for use in human therapeutic or diagnostic applications.

Importance

Carbamylation is a spontaneous nonenzymatic modification of proteins and amino acids by urea-derived isocyanate, which is generally present in human serum and is increased in uremic patients (Kraus and Kraus, 2001).

Proteins carbamylated at lysine or the terminal protein amino acids may play an important role in Chronic renal failure subjects in the development of atherosclerosis and cardiovascular diseases (Raine et al., 1991; Culleton et al., 1999).

Culleton BF, Larson MG, Wilson PW, Evans JC, Parfrey PS, Levy D. Cardiovascular disease and mortality in a community-based cohort with mild renal insufficiency. Kidney Int 1999; 56: 2214–9.

Kraus LM, Kraus AP Jr. Carbamoylation of amino acids and proteins in uremia. Kidney Int Suppl 2001; 78: S102–7.

Raine AE, MacMahon SH, Selwood NH, Wing AJ, Brunner FP. Mortality from myocardial infarction in patients on renal replacement therapy. Nephrol Dial Transplant 1991; 6: 902.

Citations

Academy Bio-Medical Company，Inc.专营人类脂蛋白，载脂蛋白和多克隆抗体。以可承受的价格制造和提供高质量的抗体。

自1995年以来，该公司一直以研究试剂为心血管和动脉粥样硬化研究界提供支持。我们自豪地提供致力于脂蛋白，载脂蛋白及其氧化修饰产品领域研究的抗体和试剂。我们的抗体产品得到我们技术服务专家的全面支持。