*The products are for research or manufacturing use only, not for use in human therapeutic or diagnostic applications.

Importance

Plasminogen contains 810 amino acid residues. It is a single chain glycoprotein with m.w. 90 kDa (Robbins et al., 1967), soluble in water; prepared from plasma that has been shown by certified test to be negative for HBsAg and for antibodies to HIV and HCV.

Plasminogen is the inactive precursor of the protease plasmin. Plasminogen is activated by the action of either tissue plasminogen activator (tPA), which primarily activates the fibrinolytic (thrombolytic) activity of plasmin, or urokinase plasminogen activator (uPA), which is associated with extracellular matrix remodeling and cell migration.

Robbins, K. C., L. Summaria, B. Hsieh, and R. J. Shah. “The peptide chains of human plasmin. Mechanism of activation of human plasminogen to plasmin.” J Biol Chem. 242.10 (1967):2333-42. 

Academy Bio-Medical Company，Inc.专营人类脂蛋白，载脂蛋白和多克隆抗体。以可承受的价格制造和提供高质量的抗体。

自1995年以来，该公司一直以研究试剂为心血管和动脉粥样硬化研究界提供支持。我们自豪地提供致力于脂蛋白，载脂蛋白及其氧化修饰产品领域研究的抗体和试剂。我们的抗体产品得到我们技术服务专家的全面支持。